Cannondale Synapse Road Bikes | The Complete 2025 Range
The Cannondale Synapse has long been a benchmark in endurance road cycling. First launched 20 years ago, it changed how riders thought about road bikes – blending race-level performance with comfort that could handle real-world roads. Six generations later, the 2025 Cannondale Synapse range continues to set the pace, offering lightweight carbon frames, aerodynamic design, and all-day comfort without compromise.
Perfect for long rides, fast-paced group sessions, or everyday adventures, the Synapse remains one of the most desirable endurance road bikes available today. With models equipped for everything from WorldTour speed to real-world versatility, the Cannondale Synapse is engineered to go fast, built to go long, and designed to keep you comfortable wherever the road takes you.
Why Choose the Cannondale Synapse?
- Real-World Performance – Lightweight carbon frames with aero tube shapes deliver speed and efficiency on rolling roads, climbs, and descents.
- Endurance Comfort – Up to 20% more compliant than previous generations, offering a smoother ride on rough surfaces.
- Smart Features – Integrated StashPort storage, SmartSense lighting and radar systems, and clearance for wide tyres make Synapse bikes versatile for all conditions.
- Perfect Fit – Cannondale’s Proportional Response Geometry ensures every rider gets the right balance of stiffness, comfort, and handling, no matter the frame size.
Cannondale Synapse Models 2025
Cannondale Synapse Carbon 1

The pinnacle of the Synapse range, designed for riders chasing elite-level performance.
- Hi-MOD carbon construction – ultra-light and responsive
- SystemBar R-One integrated carbon cockpit
- Reserve 42|49 Aero carbon wheels with DT Swiss hubs
- Shimano Ultegra Di2 12-speed electronic shifting
- Vittoria Corsa PRO Control tyres for race-ready grip
Best for: Riders wanting WorldTour performance in a road endurance package.
Cannondale Synapse Carbon 2 SmartSense

Blending speed, safety, and technology, this model redefines endurance cycling.
- Lightweight aero carbon frame with Proportional Response Construction
- SRAM Force AXS wireless electronic drivetrain
- Reserve 42|49 Aero carbon wheels
- SmartSense Gen 2 – integrated lights and Garmin radar system
- StashPort internal storage for essentials
Best for: Riders who value cutting-edge integration and safety features.
Cannondale Synapse Carbon 2

A sleek endurance machine with smooth shifting and refined performance.
- Lightweight carbon frameset with integrated StashPort storage
- Shimano Ultegra Di2 12-speed electronic shifting
- DT Swiss carbon wheels for fast all-road capability
- Fizik Vento Argo R5 saddle for comfort on long rides
Best for: Riders seeking a high-performance balance of speed and practicality.
Cannondale Synapse Carbon 3 SmartSense

Advanced endurance performance with smart safety technology.
- Carbon frameset with aerodynamic shaping and StashPort storage
- SRAM Rival AXS wireless electronic groupset
- Hydraulic disc brakes for all-conditions control
- DT Swiss E 1800 Spline wheels
- SmartSense Gen 2 integrated lighting and radar system
Best for: Riders wanting electronic shifting and advanced visibility at a competitive price point.
Cannondale Synapse Carbon 4

Smooth electronic shifting and aero comfort for everyday endurance riders.
- Lightweight carbon frameset with StashPort storage
- Shimano 105 Di2 12-speed drivetrain
- DT Swiss 470 wheels with Vittoria Rubino Pro IV 32c tyres
- Fizik Vento Argo R5 saddle
Best for: Cyclists upgrading to electronic shifting in an endurance road bike.
Cannondale Synapse Carbon 5

The entry point into the 2025 Synapse family, built with proven endurance DNA.
- Carbon frameset with StashPort storage
- Shimano 105 12-speed mechanical groupset
- DT Swiss 470 rims with durable Vittoria tyres
- Aero carbon seatpost for balanced comfort and speed
Best for: Riders looking for Synapse performance and design at the best value.
The Synapse: Road Reimagined
Whether it’s the cutting-edge Synapse Carbon 1 or the value-packed Synapse Carbon 5, every bike in the 2025 range is designed with one goal – to deliver unreal performance for real-world roads. With tyre clearance up to 42mm, integrated storage, SmartSense safety systems, and a carbon frame that weighs under 1,150g (sub-1000g in Hi-MOD), the Cannondale Synapse isn’t just keeping pace with modern endurance cycling – it’s leading it.
For riders who want speed, comfort, and versatility without compromise, the Cannondale Synapse remains one of the most complete endurance road bikes available.
Shop the full Cannondale Synapse 2025 range today and find the model that matches your ride style.
- o% Finance Options Available.
- Delivered Ready To Ride – just insert the front wheel and turn the handlebars. Only minor assembly required.
- Cycle To Work vouchers accepted.
- 5 Star Customer Service and a professional workshop for exceptional aftercare.